Efficacy of oncoplastic breast-conserving surgery combined with intraoperative radiotherapy on early breast cancer

An interesting article by Quan Liu and Jun Fang, exploring the efficacy and safety of oncoplastic breast-conserving surgery (OBCS) combined with intraoperative radiotherapy (IORT) in the treatment of early breast cancer (EBC).

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To explore the efficacy and safety of oncoplastic breast-conserving surgery (OBCS) combined with intraoperative radiotherapy (IORT) in the treatment of early breast cancer (EBC).

The clinical data of 114 EBC patients treated in our hospital from January 2014 to May 2016 were retrospectively analyzed. The patients were divided into OBCS + IORT group (OBCS group, n=32) and standard BCS (SBCS) + IORT group (SBCS group, n=82) according to different treatment methods. The operation-related indexes, the weight of breast tissues resected, the surgical margin, the postoperative cosmetic effect on affected breasts and quality of life, the incidence of postoperative complications, postoperative tumor recurrence and patient's survival were compared between the two groups.

The operation time of patients in OBCS group was significantly longer than in SBCS group, the amount of intraoperative blood loss and postoperative drainage was significantly smaller than in SBCS group, and the postoperative hospital stay was obviously shorter than in SBCS group. The incidence rates of postoperative hematoma and poor incision healing in OBCS group were obviously lower than in SBCS group. The weight of breast tissues resected, and minimum and maximum surgical margin were all evidently larger in OBCS group than in SBCS group. After operation, the excellent/good rate of breast appearance in OBCS group was significantly higher. After operation, the satisfaction with breast appearance, the score of each dimension in the short-form 36-item health survey questionnaire (SF-36) and average score in OBCS group were remarkably superior to those in SBCS group.

OBCS combined with IORT is safe and effective in the treatment of EBC, which can not only effectively ensure the surgical margin in BCS and reduce the incidence of surgical complications, but also obtain a better cosmetic effect and satisfaction with breast appearance, and improve the postoperative quality of life of patients.

Read full article here: https://pubmed.ncbi.nlm.nih.gov/33277841/ 

Jasmine Walter

Content Editor, Mark Allen Group

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