The impact of body mass index (BMI) on MRI diagnostic performance and surgical management for axillary lymph node in breast cancer

Shu-Tian Chen, Hung-Wen Lai, Wen-Pei Wu, Shou-Tung Chen, Chiung-Ying Liao, Hwa-Koon Wu, Dar-Ren Chen, Chi Wei Mok
The impact of body mass index (BMI) on MRI diagnostic performance and surgical management for axillary lymph node in breast cancer

We hypothesized that different BMI might have different impact on pre-operative MRI axillary lymph node (ALN) prediction accuracy and thereby subsequent surgical lymph node management. The aim of this study is to evaluate the effect of BMI on presentation, surgical treatment, and MRI performance characteristics of breast cancer with the main focus on ALN metastasis evaluation.

The medical records of patients with primary invasive breast cancer who had pre-operative breast MRI and underwent surgical resection were retrospectively reviewed. They were categorized into 3 groups in this study: underweight (BMI < 18.5), normal (BMI of 18.5 to 24), and overweight (BMI > 24). Patients' characteristics, surgical management, and MRI performance for axillary evaluation between the 3 groups were compared.

Our findings suggest that BMI may influence the diagnostic performance on MRI on ALN involvement and the surgical management of the axilla in overweight to obese women with breast cancer.

Read full article here: https://pubmed.ncbi.nlm.nih.gov/35193599/