Uncertainties and controversies in axillary management of patients with breast cancer

Walter P Weber, Oreste Davide Gentilini, Monica Morrow et al.
Uncertainties and controversies in axillary management of patients with breast cancer
Like

Share this post

Choose a social network to share with, or copy the shortened URL to share elsewhere

This is a representation of how your post may appear on social media. The actual post will vary between social networks

The aims of this Oncoplastic Breast Consortium and European Breast Cancer Research Association of Surgical Trialists initiative were to identify uncertainties and controversies in axillary management of early breast cancer and to recommend appropriate strategies to address them.

By use of Delphi methods, 15 questions were prioritized by more than 250 breast surgeons, patient advocates and radiation oncologists from 60 countries. Subsequently, a global virtual consensus panel considered available data, ongoing studies and resource utilization. It agreed that research should no longer be prioritized for standardization of axillary imaging, de-escalation of axillary surgery in node-positive cancer and risk evaluation of modern surgery and radiotherapy.

Instead, expert consensus recommendations for clinical practice should be based on current evidence and updated once results from ongoing studies become available. Research on de-escalation of radiotherapy and identification of the most relevant endpoints in axillary management should encompass a meta-analysis to identify knowledge gaps, followed by a Delphi process to prioritize and a consensus conference to refine recommendations for specific trial designs.

Finally, treatment of residual nodal disease after surgery was recommended to be assessed in a prospective register.

Read the full study here: Uncertainties and controversies in axillary management of patients with breast cancer - PubMed (nih.gov)

Please sign in or register for FREE

If you are a registered user on ARBS Network, please sign in